Válogatott publikációk

Harkány, T., Lengyel, Z., Soós, K., Penke, B., Luiten, P.G., Gulya, K.:
Cholinotoxic effects of b-amyloid (1-42) peptide on cortical projections of the rat nucleus       basalis  magnocellularis   
Brain Research 695, 71-75, 1995.                                                                      IF = 2.119
i = 18
 
Laczkó, I., Vass, E., Soós, K., Varga, J. L., Szárzaz, S., Hollósi, M., Penke, B.,:
Ca2+ - and Al3+ induced conformational transitions of amyloid fragment H-IIe-IIe-Gly-Leu-Met-NH2
Arch. Biochemistry and Biophysics 335, 381-387 1996.                                        IF = 2.649
i = 8
 
Laskay G., Zarándi M., Varga J., Jost K., Fónagy A., Torday C., Latzkovits L., Penke B.:
A putative tetrapeptide antagonist prevents b-amyloid-induced long-term elevation of [Ca2+]i

Biochem. Biophys. Res. Commun. 235, 479-481, 1997.                                        IF = 2.671
i = 7
 
Jancsó G., Domoki F., Sántha P., Varga J., Fischer J., Orosz K., Penke B., Becskei A., Dux M., Tóth L.,: b-Amyloid (1-42) peptide impairs blood-brain barier function after intracarotid infusion in rats.
Neuroscience Letters 253, 139-141, 1998.                                                            IF = 1.768
i = 8
 
Pákáski M., Farkas Z., Kása P. Jr., Forgon M., Papp K., Zarándi M., Penke B., Kása P. Sr.:
Vulnerability of small GABAergic neurons to human b-amyloid pentapeptide.
Brain Research 796, 239-246, 1998.                                                                    IF = 2.119
 
Harkány, T., Ábrahám, I., Laskay, G., Timmerman, W., Jost, K., Zarándi, M., Penke, B., Nyakas, C., Luiten, P.G.M. Propionyl-IIGL tetrapeptide antagonizes b-amyloid excitotoxicity in rat nucleus basalis. 
Neuroreport 10, 1693-1698, 1999.                                                                       IF = 2.262
 
Harkány, T., Ábrahám, I., Timmerman, W., Laskay, G., Tóth, B., Sasvári, M., Kónya, C., Sebens, JB., Korf, J., Nyakas, C., Zarándi, M., Soós, K., Penke, B., Luiten, PGM.: b-Amyloid neurotoxicity is  mediated by a glutamate-triggered excitotoxic cascade in rat nucleus basalis
Eur. J. Neurosci. 12, 2735-2745,  2000.                                                               IF = 3.899
 
Harkány, T., Ábrahám, I., Kónya, C., Zarándi, M., Penke, B., Luiten, P.G.M.:
Mechanism of b-amyloid neurotoxicity:perspectives of pharmacotherapy.
Rev. Neurosci. 11 , 329-382, 2000.                                                                        IF = 3.387
 
Harkány, T, O’Mahony, S., Kelly, JP., Kónya, C., Keijser, JN., Borostyánkői, ZA., Görcs, T., Zarándi, M., Penke, B., Leonard, BE., Luiten, PGM.: b-Amyloid-induced cholinergic lesions to the rat nucleus basalis bi-directinally modulate serotonergic activity in basal forebrain and cerebral cortex.
Neurobiol Dis., 8 , 667-678 (2001)                                                                IF = 4.225
 
DeMager, P.P., Penke, B., Walter, R., Harkany, T., Härtig, W.: Pathological peptide folding in Alzheimer’s disease and other conformational disorders.
Current Medicinal Chemistry 9, 1763-1780, 2002.                                                IF =4.909
 
Fassbender K., Walter S., Kühl S., Landmann R., Ishii K., Bertsch T., Stalder A.K., Muehlhauser F., Liu Y., Ulmer A.J., Rivest S., Lentschat A., Gulbins E., Jucker M., Stufenbiel M., Brechtel K., Walter J., Multhaup G., Penke B., Adachi Y., Hartmann T. and Beyreuther K.: The LPS receptor, CD14 links innate immunity with Alzheimer’s disease.
FASEB Journal , 17, U518-U532, 2003.                                                                IF = 7,252
 
Verdier Y., Zarándi M., Penke B.: Amyloid ß-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer’s disease.
J. Peptide Sci 10, 229-248, 2004.                                                                       IF = 1.471
 
Verdier, Y. Penke, B.: Binding sites of amyloid-ß-peptide in cell plasma membrane and implications for Alzheimer’s disease.
Current Protein and Peptide Science 5 , 19-31, 2004                                            IF = 1,71
 
Szegedi V, Juhasz G, Rozsa E, Juhasz-Vedres G, Datki Z, Fulop L, Bozso Z, Lakatos A, Laczko  I, Farkas T, Kis Z, Toth G, Soos K, Zarandi M, Budai D, Toldi J, Penke B.
Endomorphin-2, an endogenous tetrapeptide, protects against Abeta1-42 in vitro and in vivo.
FASEB J. 20(8), 1191-3., 2006
      
Zarándi M., Soós K., Fülöp L., Bozsó Zs, Datki Zs, Tóth G.K., Penke B.:
Synthesis of Aß(1-42) and its derivatives with improved efficiency
Peptide Sci., 2006, in press