End semester topic list


1. Spinal cord. Neurological localisation. (structure of gray matter, major tracts of posterior, lateral and anterior columns, symptomatology of spinal cord damage localisation, symptomatology of acute spinal cord transsection – time course. Syringomyelia, Brown-Séquard syndrome)

2. Muscle tone and its disturbances. (regulators of muscle tone: gamma loop, brain stem, cerebellum, basal ganglia, hypotonia, rigidity and spasticity and their causes)

3. Types of reflexes. Pathological reflexes. (tendon reflexes: reflex arch, superficial reflexes: reflex arch, reflexes associated with pyramidal laesion, frontal liberation reflexes)

4. Medulla. Neurological localisation. (macroscopic anatomy, passing tracts, cranial nerve nuclei, medial and lateral medullary syndrome)

5. Pons. Neurological localisation. (macroscopic anatomy, passing tracts, cranial nerve nuclei, symptoms of pons damage)

6. Mesencephalon. Neurological localisation. (macroscopic anatomy, passing tracts, cranial nerve nuclei, symptoms of mesenchephalon damage, Weber syndrome)

7. Cranial nerves – except CN II, III, IV, VI. (anatomy, nuclei, function, symptoms of damage).

8. Cranial nerves III, IV, VI. Pupillary reactions. (anatomy, nuclei, function, symptoms of damage of nerves III, IV and VI, pupillary reflex arch, causes of myosis and mydriasis)

9. EEG and evoked potentials. (physiology of EEG, wave types, indications of EEG. Physiology of VEP, AEP and SSEP, their indications)

10. Frontal lobe. Neurological localisation. (anatomy, functions, symptoms of frontal lobe damage/excitation)

11. Corticospinal tract. Neurological localisation. (anatomy of corticospinal tract, function, symptoms of laesion, pathological reflexes associated to pyramidal tract damage)

12. Differential diagnosis of central and peripheral palsy. (motor system – upper and lower motor neuron – anatomy, function, cranial nerves, spinal nerves, central and peripheral palsy)

13. Extrapyramidal system. Neurological localisation. (basal ganglia, interconnection, function, chorea, ballism, parkinsonism – symptoms, localisation)

14. Parietal lobe. Neurological localisation. (anatomy, functions, symptoms of parietal lobe damage/excitation)

15. Thalamus. Neurological localisation. (anatomy, function, lesion symptoms)

16. Temporal lobe. Neurological localisation. (anatomy, functions, symptoms of temporal lobe damage/excitation)

17. Limbic system. Neurological localisation. (anatomy of the limbic system – Papez ring, interconnections, symptoms of laesion, Korsakoff syndrome)

18. Occipital lobe. Neurological localisation. (anatomy, functions, symptoms of occipital lobe damage/excitation)

19. Optic system. Neurological localisation. (receptors, afferents, centers, laesion symptoms in various parts of the optic system, main causes)

20. CT and MRI in neurology practice. (basic physics of these methods, indications, comparison of CT and MRI scans in neurology, appearance of most common laesions – bleeding, ischaemia, tumor)

21. PET, SPECT, arteriography (DSA) and Doppler ultrasound in neurology practice. (basic physics of PET, SPECT, DSA and doppler, indications in neurology)

22. ENG and EMG in neurology practice. (ENG, EMG: how it is done, indications, interpretation of results. Repetitive nerve stimulation, indications)

23. Cerebrospinal fluid: production, circulation, absorption and their disturbances. (CSF: composition, production, circulation, absorbtion, types of hydrocephalus and their diagnosis)

24. Facial palsy. (facial nerve upper and lower motor neuron – anatomy, causes of central facial palsy, causes of peripheral facial palsy, symptoms of central and peripheral facial palsy)

25. Supranuclear gaze disturbances. (nuclei of cranial nerves involved in eye movements, FLM, pontine gaze center, frontal horizontal gaze center, laesion symptoms, Parinaud syndrome)

26. Alteration of vigility. Brain death. (physiology of vigility, definition of somnolence, stupor, coma, GCS, alteration of vigility due to brain stem/cortical damage, differentiation, brain death)

27. Cerebellum. Neurological localisation. (functional anatomy of cerebellum – vestibulocerebellum, spinocerebellum, cerebrocerebellum – input, output, function, cerebellar symptoms)

28. Aphasias. (defintion, motor aphasia, sensory aphasia, anomic aphasia, conduciton aphasia, global aphasia – symptoms, localisation of the lesion)

29. Sensory system and its disturbances. (spinothalamic and Goll-burdach tracts: anatomy, function, laesion symptoms, syringomyelia, dorsal column symptoms)

30. Functional anatomy of the autonomic system and its disturbances. (anatomy of sympathetic and parasympathetic system – preganglionar neuron, postganglionar neuron, neurotransmitters, receptors, effects on different organs, symptoms of lesions)

31. Brain circulation. (basic characteristics of brain circulation, regulation of global and local perfusion, symptoms of circulatory disturbances in the brain – ACA, MCA, PCA, VB)

32. Lumbar puncture, indications, lab tests. (indications, contraindications, composition of normal CSF, pathological CSF – SAH, meningitis, encephalitis, TB, Guillain-Barré syndrome, multiple sclerosis)

33. Referral of neurology patients. Evidence based medicine. (the logic of referral, definition of evidence based medicine, levels of evidence, guidelines)