2022. July 4., Monday
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Special Cell Therapy may Provide an Answer to Non-Healing Ulcers at Albert Szent-Györgyi Medical Center, University of Szeged

Difficult or non-healing venous leg ulcers and diabetic leg ulcers can also benefit by a cell therapy procedure that doctors at the Albert Szent-Györgyi Medical Centre of University of Szeged for Department of Dermatology and Allergology are using in a clinical research project. After years of research and development, the therapy will be introduced in Hungary for the very first time through the University of Szeged.

The adipose tissue of the human body contains many cell types with regenerative properties, in addition to fat. Over the last decade, research and clinical trials have been launched worldwide to find out how these cells can be harnessed for new therapeutic applications. Over time, the results have led to the development of a number of therapeutic approaches. Some are already routinely used and others are available through clinical trials. However in Hungary, there are only a few of these procedures currently available. The Albert Szent-Györgyi Medical Centre of University of Szeged for Department of Dermatology and Allergology, as the leading centre in the region, would like to change this by providing care, initially for this region.


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The current clinical trial is open to 15 patients from the Department of Dermatology and Allergology, Albert Szent-Györgyi Medical Centre of University of Szeged. Ten of them suffer from venous leg ulcers and five from diabetic leg ulcers.


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"In this clinical trial, we use a special technology to extract cells from fat tissue, procured during plastic surgery, which is then injected into patients. In other words, patients get their own cells back, injected around the hard-to-heal ulcer. These cells are expected to trigger healing processes that assist wounds and ulcers to close and exfoliate. This process can take weeks, and the results of the clinical trial will reveal up to six months later if the same procedure is required to be repeated. In the case of the clinical trial, the technology required for the processing of adipose tissue (Lorem Cytori, Celution) was provided by Humancell Technologies Ltd., within the framework of scientific and strategic cooperation. The company is also committed to the introduction and application of cell therapy procedures in Hungary. This technology is already used in many countries, but The University of Szeged would like to introduce it as a therapy for the first time in Hungary." - Said Dr Balázs Bende, principal investigator of the clinical trial.


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The idea to launch a clinical trial was conceived seven years ago, and over this period of time, the necessary infrastructure and human resources have been carefully co-ordinated through collaborations and tenders. The research and development test results have led to the establishment of the Personalised Medicine Research Infrastructure at the University of Szeged, covering the entire innovation and healthcare value chain, from disease diagnosis to the development of new therapies and bedside applications. The first result of this development is the ongoing clinical trial.


Prof. Dr. Lajos Kemény, head of the Translational Biomedicine Competence Centre, is the head of research, while Dr. Zoltán Veréb and the staff of the laboratory under his leadership are responsible for the production of stem cells. The clinical trial is led by Dr Balázs Bende. The therapy is carried out by plastic surgeons and dermatology specialists of the SZTE SZAKK, assisted by more than 10 medical staff.


SZTEinfo

Photos by: István Sahin-Tóth

SZTE Experience

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Nikki - Faculty of Health Sciences and Social Studies

My name is Nikki and I am from Iran. Currently I am a second year student studying Physiotherapy at the University of Szeged. I really like the Environment of Szeged as it is a true University City where you can meet people from around the world. I consider Szeged as my second home since I have established my own path here and I have a lot of friends who make me feel home. The reason why I came to Szeged is because I was informed by one of my friends about the fact that the University degrees are EU accredited and will help me to reach my goals and open doors for future job opportunities. Once I have obtained my degree, I would like to stay in Hungary and pursue a post graduate program. Later on I will seize the opportunity to gain some job experience in my field here in Hungary before I hold my ground in Europe.

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Ahmad Adha - Faculty of Humanities and Social Sciences

I am Ahmad Adha from Indonesia and currently a 3rd year student in Theoretical Linguistics PhD program. I chose the University of Szeged (SZTE) as my study destination because it is located in the center of the town and it is also the highest ranked university in Hungary. The university staff and the professors were very accommodating and understanding when I decided to change the program that suits my research topic. I am so glad that I can be a part of my current department, and of course SZTE, since it is also the Center of Pragmatic Research which aims to promote advanced linguistic pragmatic research with international collaborations. After graduating, I wish to continue to work in my academic field as a professor and a researcher. My advice for prospective SZTE students is to choose a university with a good academic reputation that fits their passion.

 

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