1. The structure and working principle of the immune system. Central and peripheral lymphoid organs. (Buzás Krisztina)

2. Characteristics of innate immunity. The relationship between innate and adaptive immunity. (Roberta Fajka-Boja)

3. Complement system. Cell types and mediators involved in inflammation and acute phase response. (Roberta Fajka-Boja)

4. The structure of MHC molecules, polymorphism. Antigen presentation. Development of T and B cells. (Ágnes Czibula)

5. Antigen recognition function of T lymphocytes. The T cell mediated immune response. T cell types, their effector functions. (Ágnes Czibula)

6. B lymphocytes. B cell activation, antigen-dependent differentiation of B cells. The structure of antibodies, antibody-mediated effector functions. (Prof. Attila Bácsi)

7. TEST FOR RECOMMENDED GRADE (1. MTO)

8. Immune responses against extracellular pathogens. Immune responses against intracellular pathogens. Immunescape. Immunological memory. Vaccination. (Dobra Gabriella)

9. Autoimmunity. Peripheral and central immune tolerance. (Prof. László Kovács)

10. Types and characteristics of hypersensitivity reactions. Allergic reactions. (Judit Danis)

11. Transplantation, pregnancy immunology. (Gyukity-Sebestyén Edina)

12. Tumor immunology. Immunotherapies and their role in tumor therapy. (Krisztina Buzás)

13. TEST FOR RECOMMENDED GRADE (2. MTO)

14. Basic immunology methods. Monoclonal antibodies, Immunodiagnostics. (Gabriella Terhes)

Examination of the learning outcomes:

Attendance at lectures is mandatory.

Requirement of the admission to the exam: no more than 3 absences allowed in the classroom teaching.

In case of absence, the absence can only be justified in the manner specified in the Study Rules of the TVSZ and SZAOK.

In case of more than 3 absences, the student is not allowed to take the exam!

MTOs:

Two MTOs will be written during the semester.

1. MTO: 2025. March 28. during the lecture (mandatory)

2. MTO: 2025. May 21. 18:00, NOT mandatory; Walter Károly room (Pedriatic Health Center. Korányi fasor 14-15.)

In case that the average result of the two MTOs reaches 80% the grade of the colloquium is offered at the end of the semester.

If 80% is reached, it means the offered grade 4 (good), if the averaged result of the two MTOs reaches 90%, the offered grade is 5 (excellent).

If you don’t reach 80% in the MTO, there will be NO negative consequences.

Retake of the MTOs is not possible.

Exam:

The first and second exam will be written. You need to reach 60% to pass the exam.

The grades are determined as follows:

0-59% failed (1)

60-69% pass (2)

70-79% satisfactory (3)

80-89% good (4)

90-100% excellent (5)

The second repeated - your third - exam and any further exams are oral.

The potential improvement of the examination will be oral (in case somebody wants a better grade than the offered, for example 5 instead of 4).

The unsatisfactory semester mark can be corrected during the examination period in accordance with the examination regulations.

The basics of the exam:

The teaching material dealt with in the lectures.

Recommended specialist literature:

Janeway: Immunbiology (Taylor&Francis, 2007)

Abul Abbas Andrew Lichtman Shiv Pillai: Basic Immunology (Elsevier, 2019)

Abul Abbas Andrew Lichtman Shiv Pillai: Cellular and molecular immunology (Elsevier, 2017)